CCR5 抗体 (AA 6-20)
Quick Overview for CCR5 抗体 (AA 6-20) (ABIN265000)
抗原
See all CCR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-20
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特异性
- This antibody reacts to CCR5 (6-20) (CD195).
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纯化方法
- Antigen Immunoaffiinity Chromatography
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免疫原
- Synthetic peptide corresponding to amino acids 6 to 20 of Human CCR5.
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亚型
- IgG
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anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibody
CCR5 适用: 人 IHC (fro) 宿主: 小鼠 Monoclonal 12D1 unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibodyCCR5 适用: 人, 大鼠 WB, ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 6G11D1 unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 19-34), (N-Term) antibodyCCR5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 201-300) antibodyCCR5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibodyCCR5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) antibodyCCR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) antibodyCCR5 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-22) antibodyCCR5 适用: 人 WB, ELISA, FACS, IP, ICC 宿主: 小鼠 Monoclonal T21-8 unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (pSer336) antibodyCCR5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (Middle Region) antibodyCCR5 适用: 人, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0.25 to 0.5 μg/mL. Detects an approximately 40 kDa band in THP-1 whole celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline solution containing 0.02 % Sodium Azide as a preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.
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- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
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别名
- CD195 / CCR5
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背景
- Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors1,2. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells3,4. CCR5 is required for the infection by HIV-1, HIV-2, and SIV1,2. The b-chemokines RANTES, MIP-1a and MIP-1b are the ligands for CCR5 and prevent infection by M-tropic HIV-13-5. CXC5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells6,7. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites8. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor
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基因ID
- 1234
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NCBI登录号
- NP_000570
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UniProt
- P51681
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
抗原
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